In August 2025, the American College of Cardiology (ACC) released updated guidance on vaccinations specifically for individuals living with heart disease. These recommendations consolidate previous guidance from expert organizations such as the American Heart Association (AHA) and the Centers for Disease Control and Prevention (CDC). The new guidelines emphasize the critical role vaccines play in preventing serious infections that can exacerbate cardiovascular conditions and increase the risk of complications like heart attacks, heart failure, and strokes.

Why Vaccinations Are Crucial for Heart Health
People with cardiovascular disease are particularly vulnerable to infections. Respiratory illnesses such as influenza, COVID-19, and respiratory syncytial virus (RSV) can place significant stress on the heart, increasing the likelihood of hospitalization and serious cardiovascular events. In addition, infections themselves can worsen underlying heart conditions, leading to prolonged recovery times, higher morbidity, and in severe cases, mortality. Maintaining up-to-date vaccinations offers a crucial layer of protection for this high-risk population.
The Five Essential Vaccines
The ACC highlights five vaccines that are especially important for people with heart disease:
- Influenza (Flu) Vaccine: Recommended annually, the flu shot lowers cardiovascular risks, including mortality. People with heart disease gain significant protection as influenza can trigger heart attacks and heart failure exacerbations.
- Pneumococcal Vaccine: A one-time vaccine advised for all adults with cardiovascular conditions. It protects against pneumonia, bacteremia, and meningitis, reducing the likelihood of severe infections that could strain the heart.
- COVID-19 Vaccine: Now recommended as a seasonal shot, COVID-19 vaccination helps prevent virus-induced heart complications, including myocarditis, pericarditis, strokes, atrial fibrillation, and long COVID symptoms.
- Respiratory Syncytial Virus (RSV) Vaccine: Recommended as a single dose for adults aged 50–74 with heart disease and universally for those 75 and older. RSV can cause severe lower respiratory tract infections, which pose a significant risk for individuals with cardiovascular disease.
- Shingles Vaccine: A two-dose vaccine for adults aged 50 and above. Shingles can increase the risk of stroke and heart attacks, making vaccination a vital preventive measure.
Research shows that patients with heart disease derive greater benefit from vaccines compared to those without heart conditions. This heightened benefit reflects the increased vulnerability of the heart to infection-induced stress and inflammation.
Overcoming Barriers to Vaccination
Despite clear recommendations, barriers to vaccination persist. Many patients do not receive vaccine guidance from their primary care providers or cardiologists, and some may lack access to healthcare, particularly those who are underinsured. Time constraints, mobility issues, or logistical challenges can also prevent individuals from receiving timely vaccinations.
The ACC recommends that cardiology clinics routinely offer vaccines on-site, allowing patients easier access and reducing missed opportunities. This approach can help improve vaccination coverage and protect more patients from infection-related complications.
Addressing Concerns About Side Effects
Vaccine hesitancy remains a concern, particularly among older adults with chronic health conditions. Patients often worry about side effects, ranging from mild discomfort to rare serious reactions. Healthcare providers play a crucial role in addressing these concerns by explaining the safety, efficacy, and potential cardiovascular benefits of each vaccine. Open discussion with cardiologists or trusted medical professionals allows patients to make informed decisions based on evidence rather than fear.
Practical Advice for Patients
Individuals with heart disease should review their vaccination status annually and maintain an updated schedule. Coordinating vaccines with routine cardiology visits can streamline care and reduce stress. Understanding the role of each vaccine in preventing infections that could worsen heart health empowers patients to actively participate in their own preventive care.
By improving vaccination rates, clinicians and patients together can lower the risk of severe infection, reduce hospitalization rates, and minimize cardiovascular complications. Combining vaccination with ongoing management of heart disease—including medications, lifestyle modifications, and regular monitoring—provides a comprehensive strategy for maintaining heart health.

Key Takeaways
- Vaccinations are an essential preventive measure for individuals with cardiovascular disease.
- The five highlighted vaccines—flu, pneumococcal, COVID-19, RSV, and shingles—target infections that pose significant risks to heart health.
- Overcoming barriers such as access, awareness, and hesitancy is crucial for improving vaccination coverage.
- Patients should engage in open dialogue with healthcare providers to understand vaccine benefits, risks, and scheduling.
- Integrating vaccinations into regular cardiology care offers a practical, proactive approach to reducing infection-related complications and supporting long-term cardiovascular health.
Staying informed about vaccinations and actively maintaining an up-to-date immunization schedule is a simple yet highly effective strategy for safeguarding heart health, enhancing quality of life, and preventing avoidable complications in people living with cardiovascular disease.